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The health of the UK workforce is deteriorating. According to the Health & Safety Executive, work related anxiety, stress, and depression are the leading cause of work absenteeism reflecting an aging workforce and rise in long-term health conditions (1). The Office of National Statistics estimates workforce absence rose to 4.4 days per worker in 2024 resulting in 148.9 million working days lost (2). In their Future of Wellbeing (2023), Deloitte reported 74% of employees were more concerned with improving their wellbeing than progressing their career and, half of working parents felt that concerns about their children’s mental health had impacted their performance at work (3).

 

 It is known that employers who prioritise employee wellbeing see measurable benefits including higher customer engagement, productivity and profitability with lower turnover, absenteeism and safety incidents (4). Unsurprisingly, employees who feel supported and valued are more innovative, collaborative and dedicated to organisational goals and 32% less likely to seek job opportunities elsewhere (5). Deloitte estimate a 5-fold return on investment, with every £1 spent on supporting employees’ mental health and wellbeing delivering £4.70 benefit (6).

 

"Every £1 spent on employees' mental health delivers £4.70 benefit"


Understanding of the impact of metabolic health on physical and mental illness has accelerated over the last 10 to 15 years, initiated by the groundbreaking work of Professor Roy Taylor in type 2 diabetes. His 2021 Counterpoint study demonstrated that it is possible to undo type 2 diabetes, through significant weight loss, using low calorie soups and shakes (7). He showed that aggressive dietary intervention was able to achieve much better results than long term medication to manage high blood glucose levels removing the risk of patients developing long term complications. This is particularly significant because type 2 diabetes is the final stage of a condition called insulin resistance known to be the root cause of most chronic diseases including obesity, high blood pressure, coronary heart disease, polycystic ovary syndrome (PCOS), some cancers and many mental health disorders (8).

 

Dr David Unwin, a GP from Southport, has shown that remission is also achievable by eating real food. His low carbohydrate approach encourages patients to base meals on nutrient dense foods which don’t spike their blood glucose levels such as meat, fish, eggs, pulses, nuts cheese, vegetables and some fruits and minimising starchy and sugary carbohydrates. His results confirm early intervention is crucial, with 77% of patients achieving remission when the diet is adopted within the first 12 months after diagnosis (9) and 93% of those with prediabetes reversing the condition (10).

 

"77% patients with type 2 diabetes achieved remission with diet alone"


There is a rapidly growing body of evidence that mental health disorders respond well to a real food approach, as these too stem from insulin resistance. Diets high in refined carbohydrates and processed foods drive inflammation, oxidative stress impacting energy metabolism in the brain (11). A very low carbohydrate or ketogenic diet provides an alternative energy source (ketones) supporting neurotransmitter and mitochondrial function improving depression, bipolar disorder and psychosis (12).

 

It's clear eating energy dense, highly palatable food products, in combination with sedentary lifestyles, are driving overconsumption and weight gain. This leads to central obesity, where visceral fat deposits around and inside organs such as the liver, cause insulin resistance and a host of metabolic diseases. The National Diet and Nutrition Survey estimate 57% of total energy intake in adults in the UK is from ultra processed foods (UPF) (13). More worryingly it constitutes 75% of energy intake in children and 83% in adolescent diets. Ironically, the impact of poor work environment is most evident in NHS hospitals with staff absence rates of 4.7%, more than twice the national average. Limited access to fresh food, promotion of UPF and confectionary gifts from patients, high-pressure jobs, shift work, and constant organisational restructuring promotes widespread metabolic ill health.

 

While most people find UPF tempting, 14% of adults and 12% children suffer from UPF use disorder where their dopamine response is hijacked by sugar and refined grains (14). This food addiction and constant intrusive thoughts about food, leads to cycles of cravings, compulsion to eat specific foods such as milk chocolate, ice cream or bread then guilt, despite knowing that eating these foods is harming their health. A reduction in “Food Noise” is often cited by people using the new GLP-1 jabs for weight loss, raising awareness of the relentless impact this type of food has on many people (15). Many users are unaware that GLP-1 hormones are released in the gut naturally in response to eating real, unprocessed foods and that changing their diet may have be sufficient to achieve the results they desired.

 

The workplace is perfectly placed to have a positive impact on population health due to the length of time people spend there, the controlled food environment and opportunity to establish a culture of health improvement. A study investigating office cake found employees wanted cake to be less visible and available at work, and that it was the social engagement they enjoyed more than the consumption of sweet treats (16). A healthy workforce is nurtured over time through tiny nudges, routines and habits. According to Deloitte, wellbeing in the workplace has an opportunity to utilise holistic, proactive, preventative and data driven outcomes to redefine the concept of thriving at work to the benefit of employees, their families and the companies themselves (3).


" Redefine the concept of thriving at work for employees, their families and the company themselves"

 

Simple ways to encourage a shift towards better health at work might include:

  1. Access to fresh, whole foods throughout the day including vegetables, fruit, meat, fish, pulses, nuts, eggs and dairy.

  2. Fridges and microwaves to store and reheat real food brought from home.

  3. Limit vending machines, UPF marketing and product placement.

  4. Surveying staff on preferences for limiting communal treats and creating cake free zones.

  5. Facilitating staff recognition through non-food related activities, educating customers, clients or patients to participate in the scheme and not say thank with food.

  6. Encourage movement and exercise such as using the stairs, lunchtime walks, yoga, cycle to work schemes and on-site showers.

  7. Provide structured education to inform staff about the link between diet, lifestyle, metabolic health and chronic diseases.

  8. Subsidised cooking lessons for those wishing to learn how to prepare quick tasty meals from fresh ingredients.

  9. Provision of physical and mental health 1:1 and group coaching sessions.

  10. Subsidise health technology to encourage engagement, understanding and feedback.

  11. Prioritising work-life balance to enable regular family meals, restful evenings and annual leave, uninterrupted sleep and opportunities for hobbies and relaxation.

 

 

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References

7)        Lim EL, Hollingsworth KG, Taylor R, et al. Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia 2011; 54:2506-14

8)    Fertig BJ, Chopra D, Tuszynski JA (2022) The Four Stages of Insulin Induced Chronic Diseases of Aging. J Altern Complement Integr Med 8:232.

9)      Unwin D, Delon C, Unwin J, et al What predicts drug-free type 2 diabetes remission? Insights from an 8-year general practice service evaluation of a lower carbohydrate diet with weight loss BMJ Nutrition, Prevention & Health 2023;e000544. doi: 10.1136/bmjnph-2022-000544

10)  Unwin D, Khalid AA, Unwin J, et al. Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years. BMJ Nutrition, Prevention & Health. 2020 Nov 2;3(2):285-294

11)  Ede G, Zupec-Kania E, Masino S. Ketogenic Metabolic Therapy as a Treatment for Mental Health Disorder. Front. Nutr., 29 April 2025 Sec. Clinical Nutrition Volume 12 - 2025 | https://doi.org/10.3389/fnut.2025.1606634

14)  Gearhardt A, Bueno N, DiFeliceantonio A etc al. Social, clinical, and policy implications of ultra-processed food addiction. BMJ 2023;383

15)  Dhurandhar, E.J., Maki, K.C., Dhurandhar, N.V. et al. Food noise: definition, measurement, and future research directions. Nutr. Diabetes 15, 30 (2025). https://doi.org/10.1038/s41387-025-00382-x

16)  Walker, L. (2017). Office cake consumption in the UK: an exploration of its characteristics and associated attitudes among office workers, University of Chester, United Kingdom.


 
 
 
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Introduction

Insulin resistance is at the root cause of type 2 diabetes, heart disease, colorectal, liver, pancreas, breast, endometrial and prostate cancers, polycystic ovary syndrome (PCOS), sleep apnoea, and dementia, and yet it is rarely mentioned when discussing health. It occurs when cells in the liver, muscle and adipose tissue stop responding to the hormone insulin properly. All carbohydrates are digested into glucose and insulin pushes glucose from the blood into cells for energy or storage to tightly control blood glucose levels.  When cells become insulin resistant, the pancreas responds by producing more insulin, increasing insulin resistance and starting a cycle of hunger and weight gain which is difficult to break. Here is a quick guide to insulin resistance and how to minimise your risk of developing chronic diseases as you age.

 

Signs of Insulin Resistance

Insulin resistance is a natural physiological state during adolescence and pregnancy to promote growth. However, overconsumption of highly palatable snacks and drinks is causing a surge in insulin resistance in the population at all ages. The first signs of insulin resistance might be feeling hungry all the time, lack of energy or poor concentration, especially after eating.  Weight gain particularly around the middle, high blood pressure, fatty liver, skin tags and dark skin patches called acanthosis nigricans are also common symptoms.

 

Causes of Insulin Resistance

Where you store your fat is more important than how much you store. Everyone has a personal fat threshold for storing fat all over the body as adipose tissue and once these stores are full, excess calories overflow into the liver and surrounding abdominal tissues causing insulin resistance and associated chronic diseases. South Asian or Black ethnicities tend to have a lower fat threshold than White, meaning they develop insulin resistance at a comparatively lower BMI, but it is very individual. This is why some people present with insulin resistance and related diseases whilst still a normal weight. Hyperpalatable ultra-processed foods rich in sugar and refined starches are designed and marketed to drive over consumption causing raised insulin levels. This coupled with our sedentary and high pressure lifestyles leads to weight gain and, once our personal fat threshold becomes exceeded, insulin resistance results.

 

How to measure Insulin Resistance

There are tests for insulin resistance, but they are expensive and rarely done in the NHS. However, there are lots of markers which are easy to check. The quickest is a simple waist circumference measurement.  Your waist should be less than half your height which you can test using a piece of string! Raised blood pressure is also a good indicator of insulin resistance, so are two blood lipid measurements triglycerides which are a type of fat in the blood and High Density Lipoprotein (HDL) often known as good cholesterol. Having 3 or more markers is called metabolic syndrome but having any of these markers shows that it is likely you have insulin resistance.


Markers of Insulin Resistance

Indication of Increased risk

Increased Waist Circumference

Men >94cm Women >80cm Asian Men >90cm

Raised Blood Pressure

>130/80mmHg or on medication to lower

Raised Triglycerides

>1.7mmol/l or on medication to lower

Raised High Density Lipoprotein HDL

Men <1.0mmol/l Women <1.2mmol/l

Raised Fasting Blood Glucose

>5.6mmol/l

 

If insulin resistance is not tackled, it is a lottery as to which metabolic diseases you may develop. You may be predisposed to one disease over another depending on your genes whether heart disease, diabetes, cancer, or dementia. As the pancreas tires and becomes unable to produce enough insulin to overcome the resistance, blood glucose levels will start to rise. At this point prediabetes or type 2 diabetes is diagnosed often decades after insulin resistance first started.

 

How to improve Insulin Resistance

The good news is that in most cases insulin resistance can be reversed completely, or at least improved significantly, through diet and lifestyle changes. Losing your excess fat around the middle and enabling your cells to become more sensitive to insulin is key. This is best done through weight loss by improving what and when you eat but increasing exercise, stopping smoking, reducing stress levels and prioritising sleep are also very helpful.


It is best to think of this as adopting a healthier lifestyle rather than 'going on a diet' as its important to make changes that are sustainable. Here are 5 important pointers:


1)        Reduce ultra-processed food (UPF) and eat whole food whenever possible.

Avoid snacks, drinks and ready prepared foods high in sugar, salt, processed fats and starches which are designed to make you overeat them. Buying food as raw ingredients and cooking them from scratch is the best approach and with a bit of planning can be more economical too.

 

2)        Prioritise protein and fibre

 Whether you eat meat, fish, eggs, dairy, pulses or alternative protein sources aim for 1.5g of quality protein per kg ideal body weight. For example, if your ideal weigh is 80kg, you should be eating around 160g of protein each day. Fruit and vegetables, whole grains, nuts and seeds contain fibre for a healthy digestive tract. Remember that tropical fruits and all fruit juices contain a lot of sugar.

 

3)        Try to consume all your meals within a shorter window.

 Restricting the time window when you eat is called Time Restricted Feeding and evidence shows that the body likes to have time to process meals and utilise its energy reserves rather than constant snacking. For example, if you eat breakfast at 9am and finish your dinner by 7pm this is a 10-hour window for eating leaving 14 hours of fasting until your next meal. Fasting for longer can be particularly helpful when trying to lose weight as it allows time for insulin levels to normalise and fat reserves to be used as fuel.

 

4)        Incorporate aerobic and weight bearing movement into each day.

 Aerobic exercise such as walking, cycling, swimming, dancing and running help reduce insulin resistance by raising metabolic rate and using up excess glucose from the blood. However, strength training is also very important to build muscle and reduce muscle wasting due to aging or weight loss. Rather than think of exercise as a bolt on, try to incorporate it into your routine such as taking the stairs at work, parking further from your destination or doing some squats whilst brushing your teeth!

 

5)        Nurture yourself in nature

Despite our incredible achievements as a species, human bodies are designed for prehistoric life. Ensuring we value sleep, community, relationships, managing stress, relaxation, hobbies and interests and connecting with nature will keep our circadian rhythms, hormones, basic drives and instincts running smoothly and reduce our risk of developing insulin resistance and associated chronic diseases.


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References

1) Fertig BJ, Chopra D, Tuszynski JA (2022) The Four Stages of Insulin Resistance Induced Chronic Diseases of Aging. J Altern Complement Integr Med 8: 232.

2) Taylor R, Barnes A, Hollingsworth K et al (2023) Aetiology of Type 2 diabetes in people with a normal body mass index: testing the personal fat threshold hypothesis. Clin Sci (Lond) 137(16) 1333-1346

3) Lonnie M, Hooker E, Brunstrom JM, et al. Protein for Life: Review of Optimal Protein Intake, Sustainable Dietary Sources and the Effect on Appetite in Ageing Adults. Nutrients. 2018 Mar 16;10(3):360.

4) Ding C, Chan, Z, Magkos F. Lean, but not health: the metabolically obese normal-weight phenotype. Current opinion in Clinical Nutrition and Metabolic Care 19(6):0408-417 2016

5) Antoni R, Johnston K, Collins A, Robertson MD. Effects of intermittent fasting on glucose and lipid metabolism. Proceedings of the Nutrition Society. 2017;76(3):361-368

6) Szablewski L. Insulin Resistance: The Increased Risk of Cancers. Curr Oncol. 2024, 31 998-1027




 
 
 

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